A Flagship Pioneering Company

About Us

Who we are. What we do. And why it matters.

We work at the frontier of programmable medicines. We power our bioplatform and product candidates by harnessing evolution and AI. We operate with purpose and urgency on behalf of people everywhere. We aim to generate life-changing impact for the world.

Charting a new course

Sail Biomedicines was formed in October 2023, uniting first-in-category technologies from across the Flagship Pioneering ecosystem, and bringing more than eight years of combined data and multi-product platform-building to Sail.

This included the first platform to leverage a chemical code of Natural NanoParticles (NNPs) that are designed to enable directed and repeatable deployment of RNA to cells and tissues of choice; eRNA™, a new class of synthetic, translatable, and stable RNA that can be programmed for durable expression of proteins inside the body; and proprietary generative AI technologies that are helping to supercharge Sail’s efforts.

Leadership

Guillaume Pfefer

,
Ph.D., M.B.A.
Chief Executive Officer

Trevor Hallam

,
Ph.D.
Chief Scientific Officer

Kerry Benenato

,
Ph.D.
Chief Platform Officer

Igor Matushansky

,
M.D., Ph.D.
Chief Medical Officer

Barbara Bispham

,
J.D.
General Counsel

Ewen Cameron

,
Ph.D.
VP, Head of RNA and Discovery Technologies

Amy Espeseth

,
SVP, Head of Integrative Biology

Paul Froisland

,
M.B.A.
SVP, Head of Human Resources

Rafal Kowalczyk

,
M.B.A.
VP, Head of Finance

Rajesh Ramaswamy

,
Ph.D.
SVP, Head of Machine Learning and Artificial Intelligence Strategy

Nick Srikanth

,
M.B.A.
VP, Head of Strategy

Mark Umbarger

,
Ph.D.
VP, Head of Digital

Marc Wolfgang

,
M.S.
SVP, Head of Technical Development & Operations

Board

Stephen Berenson

,
Chairman of the Board

John Mendlein

,
J.D., Ph.D.
Board Member & Founding Team Member

Avak Kahvejian

,
Ph.D.
Board Member & Founding Team Member

Guillaume Pfefer

,
Ph.D., M.B.A.
Chief Executive Officer & Founding Team Member

Pablo Cagnoni

,
M.D.
Board Member

Wendy Chung

,
M.D., Ph.D.
Board Member

Frank D'Amelio

,
M.B.A.
Board Member

Paula Hammond

,
Ph.D.
Board Member

Sheri McCoy

,
M.S., M.B.A.
Board Member

Mary Szela

,
M.B.A.
Board Member

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